At 1850 central time, a Dassault Falcon lost power on approach to Lambert-St. Louis International Airport and was ditched into the Mississippi River. The two pilots suffered serious injuries. The airplane had departed Del Rio, Texas, about 2:20 before the accident on a Part 135 cargo flight. The airplane flew the ILS Rwy 30R approach, but missed. As the airplane was being vectored for a second approach, the pilots asked several times how far from the airport they would be going. When on base leg, the crew stated it had a fuel limitation and declared an emergency when switched to the tower frequency. No measurable quantity of fuel was detected in the fuel system when the aircraft was recovered.