At approximately 2010 Central time, the airplane impacted terrain about eight miles northeast of the Monroe Regional Airport, Monroe, La. Both occupants, each of whom held a Commercial pilot certificate, received fatal injuries. The aircraft was destroyed. The instrument proficiency flight had departed about 30 minutes prior to the accident and was being operated in instrument conditions. After multiple approaches, one pilot had to execute a missed approach due to a failure to maintain a correct approach track. The aircraft was cleared for another instrument approach, but the pilot again had to execute a missed approach. During that missed approach, the controller gave the pilot a radar vector in order to reposition the aircraft to a location where the pilot could initiate an intercept of the localizer. While in a turn toward the assigned heading, both radar and radio contact were lost.